miRNA description for miR-21 |
miRNA accession |
miR-21 |
Species |
Homo sapiens |
miR-21 identified in exosomes derived from the following tissue/cell type |
Ascites
|
21601258
|
Dendritic cells
|
21505438
|
Malignant ascites
|
21601258
|
Mesenchymal stem cells
|
25669974
|
Pleural effusions
|
21601258
|
Serum
|
18589210
|
Serum
|
25814440
|
Serum
|
25814440
|
Serum
|
25814440
|
T cells
|
21505438
|
Experiment description of studies that identified miR-21 in exosomes |
1 |
Experiment ID |
110 |
Identified molecule |
miRNA
|
Identification method |
|
PubMed ID |
21601258
|
Organism |
Homo sapiens |
Experiment description |
Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. |
Authors |
Rupp AK, Rupp C, Keller S, Brase JC, Ehehalt R, Fogel M, Moldenhauer G, Marme F, Sultmann H, Altevogt P. |
Journal name |
GO
|
Publication year |
2011 |
Sample |
Ascites |
Sample name |
Ascites - Liver cirrhosis |
Molecules identified in the study |
Protein miRNA |
Methods used in the study |
Western blotting Immunoelctron microscopy |
|
|
2 |
Experiment ID |
117 |
Identified molecule |
miRNA
|
Identification method |
Human miRNA Microarray Kit |
|
|
PubMed ID |
21505438
|
Organism |
Homo sapiens |
Experiment description |
Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. |
Authors |
Mittelbrunn M, Gutierrez-Vázquez C, Villarroya-Beltri C, González S, Sánchez-Cabo F, González MÁ, Bernad A, Sánchez-Madrid F. |
Journal name |
NATCOM
|
Publication year |
2011 |
Sample |
Dendritic cells |
Sample name |
Dendritic cells |
Molecules identified in the study |
Protein miRNA |
Methods used in the study |
Mass spectrometry Microarray |
|
|
3 |
Experiment ID |
108 |
Identified molecule |
miRNA
|
Identification method |
|
PubMed ID |
21601258
|
Organism |
Homo sapiens |
Experiment description |
Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. |
Authors |
Rupp AK, Rupp C, Keller S, Brase JC, Ehehalt R, Fogel M, Moldenhauer G, Marme F, Sultmann H, Altevogt P. |
Journal name |
GO
|
Publication year |
2011 |
Sample |
Malignant ascites |
Sample name |
Malignant ascites - Ovarian cancer |
Molecules identified in the study |
Protein miRNA |
Methods used in the study |
Western blotting Immunoelctron microscopy |
|
|
4 |
Experiment ID |
261 |
Identified molecule |
miRNA
|
Identification method |
Next generation sequencing RT-PCR |
|
|
PubMed ID |
25669974
|
Organism |
Homo sapiens |
Experiment description |
Extracellular vesicles from bone marrow mesenchymal stem/stromal cells transport tumor regulatory microRNA, proteins,and metabolites |
Authors |
Krishna C. Vallabhaneni1, Patrice Penfornis, Santosh Dhule, Francois Guillonneau, Kristen V. Adams, Yin Yuan Mo, Rui Xu, Yiming Liu, Kounosuke Watabe, Mohan C. Vemuri and Radhika Pochampally |
Journal name |
Oncotarget
|
Publication year |
2014 |
Sample |
Mesenchymal stem cells |
Sample name |
hMSCs |
Molecules identified in the study |
Protein miRNA Lipids Metabolites |
Methods used in the study |
Western blotting Mass spectrometry RT-PCR Sequencing |
|
|
5 |
Experiment ID |
109 |
Identified molecule |
miRNA
|
Identification method |
|
PubMed ID |
21601258
|
Organism |
Homo sapiens |
Experiment description |
Loss of EpCAM expression in breast cancer derived serum exosomes: Role of proteolytic cleavage. |
Authors |
Rupp AK, Rupp C, Keller S, Brase JC, Ehehalt R, Fogel M, Moldenhauer G, Marme F, Sultmann H, Altevogt P. |
Journal name |
GO
|
Publication year |
2011 |
Sample |
Pleural effusions |
Sample name |
Pleural effusions - Breast cancer |
Molecules identified in the study |
Protein miRNA |
Methods used in the study |
Western blotting |
|
|
6 |
Experiment ID |
45 |
Identified molecule |
miRNA
|
Identification method |
|
PubMed ID |
18589210
|
Organism |
Homo sapiens |
Experiment description |
MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. |
Authors |
Taylor DD, Gercel-Taylor C |
Journal name |
GO
|
Publication year |
2008 |
Sample |
Serum |
Sample name |
Serum - Papillary adenocarcinoma of ovary |
Molecules identified in the study |
Protein miRNA |
Methods used in the study |
Western blotting 467microRNA Array |
|
|
7 |
Experiment ID |
228 |
Identified molecule |
miRNA
|
Identification method |
Total Exosome RNA and Protein Isolation Kit: qRT-PCR |
|
|
PubMed ID |
25814440
|
Organism |
Homo sapiens |
Experiment description |
An optimized procedure for exosome isolation and analysis using serum samples: Application to cancer biomarker discovery |
Authors |
Li M, Rai AJ, Joel DeCastro G, Zeringer E, Barta T, Magdaleno S, Setterquist R, Vlassov AV. |
Journal name |
Methods
|
Publication year |
2015 |
Sample |
Serum |
Sample name |
Serum - Metastatic prostate cancer |
Molecules identified in the study |
miRNA |
Methods used in the study |
RT-PCR |
|
|
8 |
Experiment ID |
229 |
Identified molecule |
miRNA
|
Identification method |
Total Exosome RNA and Protein Isolation Kit: qRT-PCR |
|
|
PubMed ID |
25814440
|
Organism |
Homo sapiens |
Experiment description |
An optimized procedure for exosome isolation and analysis using serum samples: Application to cancer biomarker discovery |
Authors |
Li M, Rai AJ, Joel DeCastro G, Zeringer E, Barta T, Magdaleno S, Setterquist R, Vlassov AV. |
Journal name |
Methods
|
Publication year |
2015 |
Sample |
Serum |
Sample name |
Serum - Prostate cancer (prostatectomy) |
Molecules identified in the study |
miRNA |
Methods used in the study |
RT-PCR |
|
|
9 |
Experiment ID |
230 |
Identified molecule |
miRNA
|
Identification method |
Total Exosome RNA and Protein Isolation Kit: qRT-PCR |
|
|
PubMed ID |
25814440
|
Organism |
Homo sapiens |
Experiment description |
An optimized procedure for exosome isolation and analysis using serum samples: Application to cancer biomarker discovery |
Authors |
Li M, Rai AJ, Joel DeCastro G, Zeringer E, Barta T, Magdaleno S, Setterquist R, Vlassov AV. |
Journal name |
Methods
|
Publication year |
2015 |
Sample |
Serum |
Sample name |
Serum - Normal |
Molecules identified in the study |
miRNA |
Methods used in the study |
RT-PCR |
|
|
10 |
Experiment ID |
115 |
Identified molecule |
miRNA
|
Identification method |
Human miRNA Microarray Kit |
|
|
PubMed ID |
21505438
|
Organism |
Homo sapiens |
Experiment description |
Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells. |
Authors |
Mittelbrunn M, Gutierrez-Vázquez C, Villarroya-Beltri C, González S, Sánchez-Cabo F, González MÁ, Bernad A, Sánchez-Madrid F. |
Journal name |
NATCOM
|
Publication year |
2011 |
Sample |
T cells |
Sample name |
J77 |
Molecules identified in the study |
Protein miRNA |
Methods used in the study |
Mass spectrometry Microarray |
|
|